Ключевые слова: adaptive, adjusted, analysis, analyzed, approach, baseline, biomarker, blinding, characteristics, clinical, compliance, controlled, data, design, development, differences, drug, efficacy, endpoints, follow up, groups, heterogeneity, insights, interpretation, intervention, medical, medicine, metrics, outcomes, patient, personalized, pharmaceutical, placebo, population, precision, protocol, randomization, randomized, recruitment, research, safety, significance, statistical, stratification, study, techniques, treatment, trial, variability,